POSS® Biomedical Films - Case Study
POSS® Poly(carbonate urea) urethane copolymers - Improve film biocompatibilty
Problem:
While functional, existing materials used in biomedical implants have some difficulties:
- Poor cell, tissue, and blood compatibility
- High protein adsorbtion (thrombogenicity)
- Poor mechanical match to tissues
- In vivo failure and long recovery times
POSS® Copolymers can be tailored to mimic real body tissues
Research conducted at University College London has shown that POSS® Poly(carbonate urea) urethane copolymers are significantly more compatable with tissues and blood that commonly used urethane, polyester, and teflon biomaterials. These POSS® copolymers are non-toxic to cells and support the growth and prolifferation of cells while inhibiting protein adsorption by conformationally deactivating any adsorbed fibrinogen. By modifying the amounts of the comonomers used, the properties of the copolymer can be tailor matched to the tissues being repaired/replaced. This improved biocompatibility leads to accelerated bone and tissue regeneration, and shorter recovery times.
Learn more about POSS® for biomedical applications . . .
Click on the images at right to see a larger picture and more information. ⇒
Download the presentations on bone regeneration or skin regeneration.
Ask a POSS® Expert how POSS® Chemicals can be used to improve your biomaterials.
